1. Tuomilehto J, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, et al. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med. 2001 May;344(18):1343-5. [ DOI:10.1056/NEJM200105033441801] 2. Thompson D, Karpe F, Lafontan M, Frayn K. Physical activity and exercise in the regulation of human adipose tissue physiology. Physiol Rev. 2012 Jan;92(1):157-91. [ DOI:10.1152/physrev.00012.2011] 3. Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, et al. A PGC1-[agr]-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature. 2012 Jan;481(7382):463-8. [ DOI:10.1038/nature10777] 4. Dunstan D. Diabetes: Exercise and T2DM—move muscles more often!.Nat Rev Endocrinol. 2011 Apr;7(4):189-90. [ DOI:10.1038/nrendo.2011.35] 5. Handschin C, Spiegelman BM. The role of exercise and PGC1α in inflammation and chronic disease. Nature. 2008 Jul;454(7203):463-9. [ DOI:10.1038/nature07206] 6. van Marken Lichtenbelt WD, Vanhommerig JW, Smulders NM, Drossaerts JM, Kemerink GJ, Bouvy ND, et al. Cold-activated brown adipose tissue in healthy men. N Engl J Med. 2009 Apr;360(15):1500-8. [ DOI:10.1056/NEJMoa0808718] 7. Pedersen BK, Febbraio MA. Muscles, exercise and obesity: skeletal muscle as a secretory organ. Nat Rev Endocrinol. 2012 Apr;8(8):457-65. [ DOI:10.1038/nrendo.2012.49] 8. Cunha A. Basic research: irisin—behind the benefits of exercise. Nat Rev Endocrinol. 2012 Jan;8(4):195. [ DOI:10.1038/nrendo.2012.11] 9. Castillo-Quan JI. From white to brown fat through the PGC-1α-dependent myokine irisin: implications for diabetes and obesity. Dis Model Mech. 2012 May;5(3):293-5. [ DOI:10.1242/dmm.009894] 10. Soori R, Asad MR, Khosravi M, Abbasian S. The Effect of Submaximal Aerobic Training on Serum Irisin Level in Obese Men; with Emphasis on the Role of Irisin in Insulin-Resistance Change. Arak Med Univ J. 2016 Jul;19(4):20-30.[Full Text in Persian] 11. Kurdiova T, Balaz M, Vician M, Maderova D, Vlcek M, Valkovic L, et al. Effects of obesity, diabetes and exercise on Fndc5 gene expression and irisin release in human skeletal muscle and adipose tissue: in vivo and in vitro studies. J Physiol. 2014 Mar;592(5):1091-10. [ DOI:10.1113/jphysiol.2013.264655] 12. Kim H-j, So B, Choi M, Kang D, Song W. Resistance exercise training increases the expression of irisin concomitant with improvement of muscle function in aging mice and humans. Exp Gerontol. 2015 Oct;70:11-7. [ DOI:10.1016/j.exger.2015.07.006] 13. Blair SN, LaMonte MJ, Nichaman MZ. The evolution of physical activity recommendations: how much is enough? Am J Clin Nutr. 2004 May;79(5):913S-20S. [ DOI:10.1093/ajcn/79.5.913S] 14. Pitsavos C, Panagiotakos D, Tambalis K, Chrysohoou C, Sidossis L, Skoumas J, et al. Resistance exercise plus to aerobic activities is associated with better lipids' profile among healthy individuals: the ATTICA study. QJM. 2009 Sep; 102(9):609-16. [ DOI:10.1093/qjmed/hcp083] 15. Volek JS, Kraemer WJ, Bush JA, Boetes M, Incledon T, Clark KL, et al. Creatine supplementation enhances muscular performance during high-intensity resistance exercise. J Am Diet Assoc. 1997 Jul;97(7):765-70. [ DOI:10.1016/S0002-8223(97)00189-2] 16. Kelley GA, Kelley KS. Impact of progressive resistance training on lipids and lipoproteins in adults: a meta-analysis of randomized controlled trials. Prev Med. 2009 Jan;48(1):9-19. [ DOI:10.1016/j.ypmed.2008.10.010] 17. Winnick JJ, Gaillard T, Schuster DP. Resistance training differentially affects weight loss and glucose metabolism of White and African American patients with type 2 diabetes mellitus. Ethn Dis. 2008 Spring;18(2):152-6. 18. Saghebjoo M, Dastigerdi S, Afzalpour ME, Hedayati M. Effects of aerobic and resistance training on plasma visfatin levels in overweight women. Koomesh. 2012 Winter;13(2):225-232 .[Full Text in Persian] 19. Ormsbee MJ, Thyfault JP, Johnson EA, Kraus RM, Choi MD, Hickner RC. Fat metabolism and acute resistance exercise in trained men. J Appl Physiol. 2007 May;102(5):1767-72. [ DOI:10.1152/japplphysiol.00704.2006] 20. Moher D, Dulberg CS, Wells GA. Statistical power, sample size, and their reporting in randomized controlled trials. JAMA. 1994 Jul;272(2):122-4. [ DOI:10.1001/jama.1994.03520020048013] 21. Pierre W, Gildas AJH, Ulrich MC, Modeste W-N, azTélesphore Benoît N, Albert K. Hypoglycemic and hypolipidemic effects of Bersama engleriana leaves in nicotinamide/streptozotocin-induced type 2 diabetic rats. BMC Complement Altern Med. 2012 Dec;12(1):264. [ DOI:10.1186/1472-6882-12-264] 22. Skovsø S. Modeling type 2 diabetes in rats using high fat diet and streptozotocin. J Diabetes Investig. 2014 Jul;5(4):349-58. [ DOI:10.1111/jdi.12235] 23. Ramzany N, Gaeini AA, Choobineh S, Kordi MR, Hedayati M. Changes of RBP-4 and insulin resistance after 8 weeks of aerobic training in type 2 diabetic rats. Metabolism and Exercise. 2016 Winter and Autumn; 5(2): 89-98.[Full text in Persian] 24. Hordern MD, Dunstan DW, Prins JB, Baker MK, Singh MAF, Coombes JS. Exercise prescription for patients with type 2 diabetes and pre-diabetes: a position statement from Exercise and Sport Science Australia. J Sci Med Sport. 2012 Jan;15(1):25-31. [ DOI:10.1016/j.jsams.2011.04.005] 25. Timmons JA, Baar K, Davidsen PK, Atherton PJ. Is irisin a human exercise gene? Nature. 2012 Aug;488(7413):E9-10. [ DOI:10.1038/nature11364] 26. Pekkala S, Wiklund PK, Hulmi JJ, Ahtiainen JP, Horttanainen M, Pöllänen E, et al. Are skeletal muscle FNDC5 gene expression and irisin release regulated by exercise and related to health? J Physiol. 2013 Nov;591(21):5393-400. [ DOI:10.1113/jphysiol.2013.263707] 27. Pedersen BK. The diseasome of physical inactivity–and the role of myokines in muscle–fat cross talk. J Physiol. 2009 Dec;587(23):5559-68. [ DOI:10.1113/jphysiol.2009.179515] 28. Pardo M, Crujeiras AB, Amil M, Aguera Z, Jiménez-Murcia S, Ba-os R, et al. Association of irisin with fat mass, resting energy expenditure, and daily activity in conditions of extreme body mass index. Int J Endocrinol. 2014;2014 :857270. 29. Cypess AM, Lehman S, Williams G, Tal I, Rodman D, Goldfine AB, et al. Identification and importance of brown adipose tissue in adult humans. N Engl J Med. 2009 Apr;360(15):1509-17. [ DOI:10.1056/NEJMoa0810780] 30. Saito M, Okamatsu-Ogura Y, Matsushita M, Watanabe K, Yoneshiro T, Nio-Kobayashi J, et al. High incidence of metabolically active brown adipose tissue in healthy adult humans effects of cold exposure and adiposity. Diabetes. 2009 Jul;58(7):1526-31. [ DOI:10.2337/db09-0530] 31. Liu T-Y, Shi C-X, Gao R, Sun H-J, Xiong X-Q, Ding L, et al. Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes. Clin Sci (Lond). 2015 Nov;129(10):839-50. [ DOI:10.1042/CS20150009] 32. Park KH, Zaichenko L, Peter P, Davis CR, Crowell JA, Mantzoros CS. Diet quality is associated with circulating C-reactive protein but not irisin levels in humans. Metabolism. 2014 Feb;63(2):233-41. [ DOI:10.1016/j.metabol.2013.10.011] 33. Ruschke K, Fishbein L, Dietrich A, Klöting N, Tönjes A, Oberbach A, et al. Gene expression of PPARγ and PGC-1α in human omental and subcutaneous adipose tissues is related to insulin resistance markers and mediates beneficial effects of physical training. Eur J Endocrinol. 2010 Mar;162(3):515-23. [ DOI:10.1530/EJE-09-0767] 34. Hondares E, Rosell M, Díaz-Delfín J, Olmos Y, Monsalve M, Iglesias R, et al. Peroxisome Proliferator-activated Receptor α (PPARα) Induces PPARγ Coactivator 1α (PGC-1α) Gene Expression and Contributes to Thermogenic Activation of Brown Fat INVOLVEMENT OF PRDM16. J Biol Chem. 2011 Dec;286(50):43112-22. [ DOI:10.1074/jbc.M111.252775] 35. Abdelmegeed MA, Yoo S-H, Henderson LE, Gonzalez FJ, Woodcroft KJ, Song B-J. PPARα Expression Protects Male Mice from High Fat–Induced Nonalcoholic Fatty Liver. J Nutr. 2011 Apr;141(4):603-10. [ DOI:10.3945/jn.110.135210] 36. Wu J, Boström P, Sparks LM, Ye L, Choi JH, Giang A-H, et al. Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human. Cell. 2012 Jul;150(2):366-76. [ DOI:10.1016/j.cell.2012.05.016]
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