Primary Extra nodular non-Hodgkin lymphoma during pregnancy is rare with occurrence rate of 0.8 in 100000 pregnancy. In this report, the case of a 19-year-old woman during week 14 of her intrauterine pregnancy with primary extra nodular non-Hodgkin lymphoma is described. The staging consisted with thyroid open biopsy. After induced abortion the subject underwent chemotherapy with CHOP regimen (cyclophosphamide, doxorubicin, vincristine, and prednisolone) for 6 cycles.