Renal poly cystic sinus is a rare disease which is bilateral and has benign course. It usually breaks out after the fifth decade of life. The cysts in this disease are mainly of lymphatic origin. They can be associated with inflammation, stone or obstruction. Unlike the multicystic and polycystic kidney in which the cysts are formed in the cortex, in this disease they are seen in the sinus of the kidneys. What makes this case unique and necessery to report is its rareness and differentiation from other renal cystic lesions. The author could not find any previous report about the coexistance of edema of mons pubis with renal polycystic sinus. This study reports a bilateral poly cystic sinus which exists with intermittent edema of mons pubis. The patient is a 24-year-old female who complained of a mild pain in the flank area with intermittent edema of the mons pubis. The patient underwent urologic and gynecologic examinations which lead to the final diagnosis of renal bilateral poly cystic sinus disease. The disease had a benign course and the patient is under observation after the biopsy.