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:: Volume 6, Issue 2 (Summer 2006) ::
J Ardabil Univ Med Sci 2006, 6(2): 137-141 Back to browse issues page
Sensitivity and Specificity of Reperfusion Arrythmia in Predicting LV Function in Patients with Anterior MI
Abstract:   (14085 Views)

Background & Objectives: Coronary artery diseases and acute myocardial infarction are among the most common causes of death worldwide. Revascularization techiques have a major role in the management of this disease. Thrombolytics especially stereptokinase have been widely used because they do not require any expertise. Stereptokinase therapy may cause reperfusion of infarct area which in turn can result in arrhythmia. This study was performed to determine the sensitivity and specificity of developing reperfusion arrhythmias in predicting left ventricle function in patients with anterior myocardial infarction.

Methods: This descriptive and cross-sectionel study was conducted on 100 patiens with acute anterior myocardial infarction who were admitted to CCU ward of Buali hospital and received stereptokinase. The patients with history of heart failure and contraindication to stereptokinase therapy and patients who had died in the first 6 hours of myocardial infarction were excluded from the study. During the first 24 hours after admission echocardiography was performed for obtaining left ventricle ejection fraction. The data were gathered and analyzed with SPSS saftware using descriptive and inferential statistics.

Results: 52% of the patients encountered arrhythmia during receiving stereptokinase,  33% of whom had normal left ventricle function and 19% encountered significant dysfunction of left ventricle. From remaining 48% who didn’t encounter arrhythmia, 21% had normal function of left ventricle and in the rest of them it was impaired.

Conclusion:This study showed that the creation of arrhythmia due to reperfusion can predict the consistency of LV functioning with a sensitivity of 61% and a specificity of 58%. Moreover, there is a meaningful relationship between reperfusion arrhythmia and continuation of left ventricle functioning after treatment with streptokinase.

Keywords: Anterior Acute Myocardial Infarction, Stereptokinase, Reperfunsion Arrythmia, LV Function
Full-Text [PDF 129 kb]   (2165 Downloads)    
Type of Study: article | Subject: Special
Received: 2005/08/22 | Accepted: 2006/07/8 | Published: 2006/10/31
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Sensitivity and Specificity of Reperfusion Arrythmia in Predicting LV Function in Patients with Anterior MI. J Ardabil Univ Med Sci 2006; 6 (2) :137-141
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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 6, Issue 2 (Summer 2006) Back to browse issues page
مجله دانشگاه علوم پزشکی اردبیل Journal of Ardabil University of Medical Sciences
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