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:: Volume 6, Issue 3 (Autumn 2006) ::
J Ardabil Univ Med Sci 2006, 6(3): 245-250 Back to browse issues page
Comparison of Diabetes Prevalence in First Degree Relatives of Patients with Type II Diabetes Mellitus, Glucose Intolerants and Controls
Reza Rastmanesh * , Rahebe Shaker , Mehrdad Shoa , Yadollah Mehrabi , Lida Navayi
, r.rastmanesh@nnftri.ac.ir
Abstract:   (7974 Views)

  Background and Objectives: Early diagnosis of diabetes can prevent many unwanted and irreversible consequences which require a lot of expenses as well as advanced treatment methods and experts. The present study set out to compare prevalence of diabetes in first degree relatives (FDR) of patients with type II diabetes mellitus (T2DM), glucose intolerants and controls.

  Methods: In This case-control research, 277 healthy subjects (129 males and 148 females) with the age of 11-95 were selected from among FDR in three groups, namely those with type II diabetes, glucose intolerants and controls and were evaluated in terms of diabetic condition. World health organization criteria were applied to recognize case(s) of diabetes and glucose intolerants.

  Results: Odds ratio of being type 2 diabetic or IGT, in FDR of patients with T2DM and subjects with IGT, 5.261 compared to controls was (with 95% CI of 2.15-12.82). Prevalence of T2DM and IGT in both male and female FDR of patients with T2DM and with IGT, was significantly higher than that of controls (p< 0.005).

  Conclusion: Significantly higher prevalence of T2DM and IGT in FDR of patients with T2DM and with IGT, compared to controls, offers a very quick and cost-effective method of diagnosing covered cases of diabetes in country's health care systems.

Keywords: T2DM, Glucose Intolerance, First Degree Relative
Full-Text [PDF 143 kb]   (1943 Downloads)    
Type of Study: article | Subject: Special
Received: 2005/09/4 | Accepted: 2006/08/27 | Published: 2007/01/24
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Rastmanesh R, Shaker R, Shoa M, Mehrabi Y, Navayi L. Comparison of Diabetes Prevalence in First Degree Relatives of Patients with Type II Diabetes Mellitus, Glucose Intolerants and Controls. J Ardabil Univ Med Sci 2006; 6 (3) :245-250
URL: http://jarums.arums.ac.ir/article-1-429-en.html


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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 6, Issue 3 (Autumn 2006) Back to browse issues page
مجله دانشگاه علوم پزشکی اردبیل Journal of Ardabil University of Medical Sciences
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