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:: Volume 22, Issue 4 (Winter 2022) ::
J Ardabil Univ Med Sci 2022, 22(4): 333-348 Back to browse issues page
Investigating Fenugreek Seed Aqueous Extract on Sperm Parameters in Selected Type II Rats
Parisa Ghahremani , Hemen Moradi Sardareh , Hashem Yaghoubi * , Neda Farazi , Asadullah Asady
Department of Biology, Ardabil Branch, Islamic Azad University, Ardabil, Iran
Abstract:   (477 Views)
Background & objectives: Fenugreek (Trigonella foenum-graecum) is one of the most ancient and well-known medicinal plants, and its useful role has been well - established in treating of many diseases. The purpose of this study was to investigate the effect of Fenugreek on spermatogenesis, total antioxidant capacity and malondialdehyde (MDA) level in male diabetic rats.
Methods: In this experimental study, 24 male Wistar rats weighing approximately 200±20 gram were used. The rats were randomly divided into 4 groups of six. group1: control group, Group2: diabetic, Group3: diabetic+Fenugreek (8gram /kg diet), group4: diabetic+Fenugreek (2gram /kg diet). This treatment continued for 4 weeks. Blood glucose, total antioxidant capacity, malondialdehyde, and sperm profiles were determined.
Results: Blood glucose in diabetic rats which received Fenugreek significantly reduced compared with diabetic animals. Fenugreek also reduced body weight and MDA level of semen (p<0.05).On the other hand, Fenugreek increased the total antioxidant capacity of semen (p<0.05) and normalized sperm profiles (p<0.05).
Conclusion: According to the present results, it can be concluded that consumption of Fenugreek extract probably reduced MDA level, body weight, and normalized sperm profile thus, Fenugreek extract can be used to treat sexual dysfunction in males.
Article number: 2
Keywords: Antioxidant, Sperm, Testis, Diabetes, Rat, Aqueous Extract of Fenugreek
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Type of Study: article | Subject: بیوشیمی
Received: 2022/05/1 | Accepted: 2022/11/14 | Published: 2022/12/31
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Ethics code: IR.IAU.ARDABIL.REC1396. 15

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Ghahremani P, Moradi Sardareh H, Yaghoubi H, Farazi N, Asady A. Investigating Fenugreek Seed Aqueous Extract on Sperm Parameters in Selected Type II Rats. J Ardabil Univ Med Sci 2022; 22 (4) :333-348
URL: http://jarums.arums.ac.ir/article-1-2106-en.html

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Volume 22, Issue 4 (Winter 2022) Back to browse issues page
مجله دانشگاه علوم پزشکی اردبیل Journal of Ardabil University of Medical Sciences
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