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:: Volume 17, Issue 3 (autumn 2017) ::
J Ardabil Univ Med Sci 2017, 17(3): 299-310 Back to browse issues page
The Effects of Eight Weeks Interval Training and Curcumin Consumption on TNF-α and BDNF Levels in Men with Metabolic Syndrome
Mortaza Salimi Avansar
Department of Physical Education and Sport Sciences, Urmia University of Technology, Urmia, Iran
Abstract:   (6354 Views)
Background & Objectives: The reduction of Brain-derived neurotrophic factor (BDNF) affects memory, learning and cognition, food intake and energy metabolism and causes behavioral disorders. Therefore, the aim of this study was to investigate the effects of eight weeks interval training and curcumin consumption on TNF-α and BDNF levels in men with metabolic syndrome.
Methods: This study was performed on 40 men with metabolic syndrome who were randomly divided into four groups, including exercise +supplement, exercise, supplement and control groups (n=10). The experimental groups did the exercise protocol and consumed curcumin supplement for eight weeks. The blood samples were collected 24 hours before the start of exercise and 48 hours after the last training session. One-way ANOVA and paired t-test were used to analyze the data. The significance level was considered to be p≤0.05.   
Results: In exercise +supplement and exercise groups, significant changes were observed in BDNF (p=0.000, p=0.004) and TNF-α (p=0.001, p=0.008) levels compared to pre-test. Also, when analyzing changes between groups, TNF-α (p=0.004) and BDNF (p=0.000) changes were statistically significant in exercise +supplement group compared to other groups.
Conclusion: Eight weeks moderate-intensity interval training combined with curcumin consumption significantly reduced inflammatory factors and increased BDNF expression.
Keywords: Interval Training, Curcumin, BDNF, TNF-α, Metabolic Syndrome
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Type of Study: article | Subject: General
Received: 2017/04/9 | Accepted: 2017/07/24 | Published: 2017/10/2
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Salimi Avansar M. The Effects of Eight Weeks Interval Training and Curcumin Consumption on TNF-α and BDNF Levels in Men with Metabolic Syndrome . J Ardabil Univ Med Sci. 2017; 17 (3) :299-310
URL: http://jarums.arums.ac.ir/article-1-1451-en.html

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Volume 17, Issue 3 (autumn 2017) Back to browse issues page
مجله دانشگاه علوم پزشکی اردبیل Journal of Ardabil University of Medical Sciences
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