Background & Objectives: Plasma lipids during pregnancy clearly increase, therefore, normal pregnancy is considered as a hyperlipidemia state. Prior studies suggest that coronary artery diseases connected with parity, but no studies have examined the relationship between parity and lipid levels in Iran. In the current study we investigated the relation between parity and lipid levels in maternal plasma in 13-23 weeks pregnant women.

  Methods: This study was done on 700 pregnant women with 18-40 years old at their 13-23 weeks gestation. Gestational age was calculated by LMP and ultrasound in early pregnancy. After obtaining informed consent from patients without exclusion criteria of the study, TC, TG, HDL-C and LDL-C was requested for them. Finally, the samples of study divided three groups according to the number of parity: nuliparous , multiparous , Grand multiparous . Data were analysed by SPSS-16 software using ANOVA and partial correlation statistical test.

  Results: With the exception of TG that showed significance difference in mean (p=0.008), the means of LDL-C (p= 0.37), HDL-C (p= 0.09) and TC (p=0.15) were not statistically significant among the 3 studied groups. Partial correlation test indicated statistically significant relationship between HDL-C with parity.

  Conclusion: The results of this study indicate decreased HDL-C levels with increasing number of pregnancies. Thus offering the program education and adequate family planning services to women in reproductive age are strongly advised.