Background & Objectives: Schizophrenia is a chronic disease with frequent periods of exacerbation & remission which influences all aspects of the patient's life, in a way that the patient never returns to his premorbid life. The goal of this survey is Study of main signs in Schizophrenia patients in Ardabil City.

Methods:�This study was a descriptive-analytic one which was done on all of the patients with schizophrenia admitted in Fatemi & Issar hospitals in 2006. A sample of 100 was selected. To study the main signs of schizophrenia in these patients, a questionnaire was used. To screen the patients with schizophrenia, MMPI test was used. The findings were analyzed by descriptive statistics & through the computer software SPSS. Also a PCA method of factor analysis was used for the hypotheses.

Results:�79 patients were male and the rest female.�The most frequent main sign in these patients was attention deficit, & social withdrawal was at the second place. Also, the most frequent type of schizophrenia was paranoid schizophrenia (44%=44 patients). The most widely used was clozapine.

Conclusion: The findings of this study have a concordance with the results of the last studies about the main signs of schizophrenia & also with DSM-IV & Bluerian & Kreaplian symptoms (except from the perception disorders).