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:: Volume 8, Issue 1 (Spring 2008) ::
J Ardabil Univ Med Sci 2008, 8(1): 45-48 Back to browse issues page
Determination of Serum IRON, TIBC and Ferrtin of Patients with Hepatitis B and Fibrosis of the Liver, A Case-Control Study
Alijan Rajabali, Dardi Qujeq , Mehrdad Kashifard
Abstract:   (4248 Views)

Background & Objective: Many factors interfere in liver fibrosis one of which is hepatitis B.The aim of our study was to determine the parameters serum iron, TIBC and ferritin of patients with hepatitis B and fibrosis of the liver

Methods: Study involved 50 cases with liver fibrosis and viral hepatitis type B (2002-2004)
and 26 controls. Iron concentration, Total iron-binding capacity and Ferritin concentration were measured by standard biochemical methods. To compare the results of the two groyps a student t-test was used and considering p< 0.05 the difference between two groups was significant.

Results: The results showed that serum ferritin increase 243.7±16.7 micro gr/L and 238.7±13.9 micro gr/L in man and women patients with chronic hepatitis B virus infection compared to the control group, 198.5±14.3 and 182.7 ±14.3 mg/L in man and women, respectively. No significant difference was found between serum Iron and TIBC in both groups. there was a significant relationship between them.

Conclusion: Increased serum ferritin concentration and liver fibrosis induced by hepatitis B virus infection. Also, determination of serum ferritin could help in diagnosis of liver fibrosis.

Keywords: Ferritin, Iron, TIBC, Liver Fibrosis, Hepatitis B
Full-Text [PDF 85 kb]   (916 Downloads)    
Type of Study: article | Subject: Special
Received: 2007/01/31 | Accepted: 2008/05/22 | Published: 2008/12/13
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Rajabali A, qujeq D, Kashifard M. Determination of Serum IRON, TIBC and Ferrtin of Patients with Hepatitis B and Fibrosis of the Liver, A Case-Control Study. J Ardabil Univ Med Sci. 2008; 8 (1) :45-48
URL: http://jarums.arums.ac.ir/article-1-342-en.html


Volume 8, Issue 1 (Spring 2008) Back to browse issues page
مجله دانشگاه علوم پزشکی اردبیل Journal of Ardabil University of Medical Sciences
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