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:: Volume 18, Issue 3 (autumn 2018) ::
J Ardabil Univ Med Sci 2018, 18(3): 279-297 Back to browse issues page
A Review of effectual factors in the Pathogenesis of Leishmania Parasites
Mahmoud Mahami-Oskouei , Mehdi Mohebali , Adel Spotin , Zahra Alizadeh
Department of Parasitology and Mycology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
Abstract:   (655 Views)
Leishmania parasites as the causative agent of leishmaniasis belong to Trypanosomatidae family. Parasite, vector, vertebrate host and environment are major factors in pathogenesis of Leishmania
Parasite dependent factors are virulence factors which exist in Leishmania species such as LPG, GP63. In recent years, the importance of these factors in the field of vaccine and drug has been considered by researchers. Sand fly biting behavior and salivary gland proteins are vector dependent factors which are effective in the Leishmania pathogenesis. Age, gender, nutrition, immune system, infectious diseases, genetic, occupation, socio-economic characteristics, and habitat are vertebrate host mediated factors. Temperature, rainfall, wind and its speed, soil, and continuous changes in climate are also environmental factors. Therefore the aim of this study was to evaluate the pathogenesis of Leishmania parasites.
 
Keywords: Leishmania, Pathogenesis, Sand Fly
Full-Text [PDF 213 kb]   (290 Downloads)    
Type of Study: review article | Subject: انگل شناسی- قارچ شناسی- حشره شناسی
Received: 2018/05/20 | Accepted: 2018/09/21 | Published: 2018/10/2
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Mahami-Oskouei M, Mohebali M, Spotin A, Alizadeh Z. A Review of effectual factors in the Pathogenesis of Leishmania Parasites. J Ardabil Univ Med Sci. 2018; 18 (3) :279-297
URL: http://jarums.arums.ac.ir/article-1-1583-en.html


Volume 18, Issue 3 (autumn 2018) Back to browse issues page
مجله دانشگاه علوم پزشکی اردبیل Journal of Ardabil University of Medical Sciences
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