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:: Volume 15, Number 1 (spring 2015) ::
J Ardabil Univ Med Sci 2015, 15(1): 66-74 Back to browse issues page
Determination of Antibiotic Resistance Pattern of Pseudomonas aeruginosa Strains Isolated from Patients with Burn Wounds
Maryam Adabi, Mahshid Talebi Taher, Leila Arbabi, Mastaneh Afshar, Sara Fathizadeh, Sara Minaeian, Niloofar Moghadam-Marageh, Ali Majidpour
Abstract:   (4769 Views)

  Background & objectives: Wound infection is a predominant cause of death in burned patients who are clearly at increased risk of nosocomial infections. Pseudomonas aeruginosa is the most common cause of burn infections and is difficult to treat because of having high level of resistance to antibiotics. The aim of this study was to perform isolation, identification and determination of antibiotics resistance pattern of P. aeruginosa strains isolated from wounds of hospitalized burn patient.

  Methods: Biochemical and molecular tests were used for identification of the P. aeruginosa and antibacterial susceptibility test was performed using disk diffusion (Kirby- Bauer) methods. Then, the minimum inhibitory concentration (MIC) was performed for four representatives of different groups of antibiotics.

  Results: Among 94 evaluated strains of P. aeruginosa, 83 isolates (88.3%) were multi drugs resistant. Based on Kirby-Bauer method, the most resistance was seen to cefepime (89.5 %) and among the antibiotics studied to determine the MIC, the most resistance was observed to ciprofloxacin (89 %).

Conclusion: These results indicate high range of resistance to different antibiotics among strains of P. aeruginosa isolated from burn wounds of patients. So, the fast and accurate measurement and evaluation of antibiotic resistance for appropriate antibiotic therapy of burned patients is imperative.

Keywords: Burn, Nosocomial Infection, Pseudomonas aeruginosa, Antibiotic Resistance, Multi-Drug Resistance
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Type of Study: article |
Received: 2014/12/15 | Accepted: 2015/03/15 | Published: 2015/03/19
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Adabi M, Talebi Taher M, Arbabi L, Afshar M, Fathizadeh S, Minaeian S, et al . Determination of Antibiotic Resistance Pattern of Pseudomonas aeruginosa Strains Isolated from Patients with Burn Wounds . J Ardabil Univ Med Sci. 2015; 15 (1) :66-74
URL: http://jarums.arums.ac.ir/article-1-783-en.html
Volume 15, Number 1 (spring 2015) Back to browse issues page
مجله دانشگاه علوم پزشکی اردبیل Journal of Ardabil University of Medical Sciences
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