[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 12, Number 3 (autumn 2012) ::
J Ardabil Univ Med Sci 2012, 12(3): 256-264 Back to browse issues page
Effect of Long Term Regular Resistance Exercise on Heart Function and Oxidative Stress in Rats
Sara Rahbar , Naser Ahmadiasl
Abstract:   (4557 Views)

  Background & Objectives: Numerous studies have been conducted to assess the effects of acute resistance exercises on the structure and the function of heart, but little works done on effects of chronic resistance exercises. So, the objective of current study was to investigate the long term effect of regular exercises on cardiac function and oxidative stress.

  Methods: Forty male Wistar rats in the weight range of 250- 300 g were used in this study. They were divided in 2 following groups: The 3 months exercises test group and control group which remained without exercises. Regular resistive exercise was carried out according to the model proposed by Tamaki et al. Test group rats exercised for three months. Finally the hearts of 10 rats in each group were taken for homogenization, oxidative stress measurement and the other ten were examined for heart function. Malondialdhyde as an index of oxidative stress and superoxide dismutase, glutathione peroxides and catalase as an indicator of antioxidant capacity with special kits were specifically measured.

  Results: Regular resistive exercise didn't significantly affect the rats' weight, but heart weight in exercise group showed a significant increase (p<0.05). There was a significant decrease in heart rate in exercise group (p<0.05). Left ventricle contraction strength and coronary flow had a significant increase in exercise group in comparison with control group (p<0.05). There was not any significant difference in Malondialdhyde and antioxidant enzymes activity.

  Conclusion: This study showed that, heart efficiency had a significant improvement under effect of regular resistive exercise. Meanwhile, regular resistive exercise didn’t have any significant effect on oxidative stress and heart antioxidant defense capacity.

Keywords: Resistance Exercise; Oxidative Stress; Rats
Full-Text [PDF 248 kb]   (1400 Downloads)    
Type of Study: article | Subject: Special
Received: 2011/11/18 | Accepted: 2012/02/14 | Published: 2012/09/22
Send email to the article author

Add your comments about this article
Your username or email:

Write the security code in the box >



XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Rahbar S, Ahmadiasl N. Effect of Long Term Regular Resistance Exercise on Heart Function and Oxidative Stress in Rats. J Ardabil Univ Med Sci. 2012; 12 (3) :256-264
URL: http://jarums.arums.ac.ir/article-1-84-en.html
Volume 12, Number 3 (autumn 2012) Back to browse issues page
مجله دانشگاه علوم پزشکی اردبیل Journal of Ardabil University of Medical Sciences
Persian site map - English site map - Created in 0.099 seconds with 786 queries by yektaweb 3455